Products
1H-Imidazole-4-carboxamide,5-amino-, hydrochloride (1:1)
Another name：
CasNo:
72-40-2
Purity：
AR 98%
Molecular Structure：
C4H6N4O.ClH
4-Amino-5-imidazolecarboxamide hydrochloride Basic Product Information
| Product Name | 4-Amino-5-imidazolecarboxamide hydrochloride | CAS | 72-40-2 |
| Synonyms | 1H-Imidazole-4-carboxamide,5-amino-, monohydrochloride (9CI);Imidazole-4-carboxamide, 5-amino-,monohydrochloride (8CI);4-Aminoimidazole-5-carboxamide hydrochloride;5-Amino-1H-imidazole-4-carboxamide hydrochloride;5-Aminoimidazole-4-carboxamide hydrochloride; | Molecular Formula | C4H7ClN4O |
| EINECS Number | 200-778-3 | Molecular Structure | |
| Appearance | Light Yellow Powder |
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| Purity | AR 98% | ||
| Supply Ability | |||
4-Amino-5-imidazolecarboxamide hydrochloride Quality documents
4-Amino-5-imidazolecarboxamide hydrochloride Appearance/Package/Shipping/Storage
package
storage condition
Store in cool & dry place,Keep away from strong light and heat
4-Amino-5-imidazolecarboxamide hydrochloride Application
4-Amino-5-imidazolecarboxamide hydrochloride literature
Development of a One-Step Synthesis of 5-Amino-1 H-imidazole-4-carboxamide
Qi, Ji,Yin, Jingjun,Li, Donghong,Chen, Song,Liu, Zhenguo
, p. 591 - 596 (2021/04/05)
An innovative and efficient synthesis of 5-amino-1H-imidazole-4-carboxamide (AIC) from commercially available hypoxanthine (～$30/kg) is described. The development of the key hydrolysis step and a practical isolation enables a highly efficient one-step manufacturing process for AIC with minimal environmental impact and significant reduction of production cost.
PROCESS FOR THE PREPARATION OF TETRAZINE DERIVATIVES
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, (2011/10/10)
The present invention provides a process for the preparation of a tetrazine derivative of formula (I), or a pharmaceutically acceptable salt thereof wherein R1 represents a hydrogen atom, a straight or branched C1-C6 alkyl group, C2-C6 alkenyl group or C2-C6 alkynyl group, which C1-C6 alkyl group, C2-C6 alkenyl group and C2-C6 alkynyl group is unsubstituted or substituted with 1, 2 or 3 substituents selected from halogen atoms, straight or branched C1-C4 alkoxy groups, C1-C4 alkylthio groups, C1-C4 alkylsulphinyl groups, C1-C4 alkylsulphonyl groups and phenyl groups, which phenyl groups are unsubstituted or substituted with one or more substituents selected from C1-C4 alkyl groups, C1-C4 alkoxy groups and nitro groups; or R1 represents a C3-C8 cycloalkyl group; and R2 represents a group of formula —(C═O)NR3R4, wherein R3 and R4 are independently selected from hydrogen atoms, C1-C4 alkyl groups, C2-C4 alkenyl groups and C3-C8 cycloalkyl groups, which process comprises: i) providing a compound N of formula (III), wherein R1 is as defined; R1—N═C═O ii) absorbing the compound of formula (III) into a solvent to obtain a solution of the compound of formula (III); iii) adding to the thus obtained solution a compound of formula (II), to obtain a compound of formula (I), as defined above, wherein R2 is as defined above; iv) decomposing any excess compound of formula (III) remaining by addition of water; and v) optionally salifying the thus obtained compound with a pharmaceutically acceptable acid, or base.
4-Amino-5-imidazolecarboxamide hydrochloride Upstream and downstream
72-40-2 Upstream product
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5-Aminoimidazole-4-carboxamide
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