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Icariin derivative

Another name:3,7-bis(2-hydroxyethyl)icaritin

CasNo: 1067198-74-6 Purity: ≥98% Molecular Structure: C25H28O8

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Icariin derivative Basic Product Information

Product Name Icariin derivative CAS 1067198-74-6
Synonyms 3,7-bis(2-hydroxyethyl)icaritin Molecular Formula C25H28O8
EINECS Number / Molecular Structure
Appearance Yellow powder
Purity ≥98%
Supply Ability 100kg / Per Month

Icariin derivative Quality documents

Icariin derivative Appearance/Package/Shipping/Storage

Package

1g-500g/bottle ,500g-1kg/Aluminum foil bag ,10KG-100KG/Cardboard drum;

Storage condition

4℃ refrigerated, sealed, away from light

Icariin derivative Application

Used in industrial production, content supplementation, identification, pharmacological experiments

Icariin derivative literature

3,7-Bis(2-hydroxyethyl)icaritin, a potent inhibitor of phosphodiesterase-5, prevents monocrotaline-induced pulmonary arterial hypertension via NO/cGMP activation in rats

Lan, Tao-Hua,Chen, Xiao-Ling,Wu, Yun-Shan,Qiu, Hui-Liang,Li, Jun-Zhe,Ruan, Xin-Min,Xu, Dan-Ping,Lin, Dong-Qun

, p. 102 - 111 (2018)

Pulmonary arterial hypertension (PAH) is a chronic progressive disease which leads to elevated pulmonary arterial pressure and right heart failure. 3,7-Bis(2-hydroxyethyl)icaritin (ICT), an icariin derivatives, was reported to have potent inhibitory activ


Synthesis and cancer cell growth inhibitory activity of icaritin derivatives

Wang, Chen,Wu, Ping,Shi, Jing-Fang,Jiang, Zi-Hua,Wei, Xiao-Yi

, p. 139 - 150 (2015)

Abstract A series of icaritin derivatives bearing carboxylic acid or carboxylic ester groups are synthesized, and their in vitro cytotoxic activity against three cancer cell lines, MCF-7, MDA-MB-435s, and A549, are evaluated by MTT assay. Several derivati


Icaritin (ICT) derivative and preparation method and application thereof

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Paragraph 0035-0039, (2019/11/04)

The invention belongs to the field of pharmaceutical chemistry, and particularly relates to an icaritin (ICT) derivative shown as the formula (II), a pharmacologically-allowable salt and preparation method of the ICT derivative, and application of the ICT


Icaritin (ICT) derivative and preparation method and application thereof

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Paragraph 0038-0041, (2019/11/04)

The invention belongs to the field of pharmaceutical chemistry, and particularly relates to an icaritin (ICT) derivative shown as the formula (I), a pharmacologically-allowable salt and preparation method of the ICT derivative, and application of the ICT


Herba Epimedii glycoside compound and use thereof

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Paragraph 0218; 0219; 0220; 0221; 0222, (2017/08/24)

The invention relates to an icariin compound and an application of the icariin compound in preparing medicines for preventing and treating fracture and osteoporosis. Particularly, the invention relates to the compound shown in a general formula (I) in the specification, a stereisomer, a stereomer, a tautomer, oxynitrides, hydrates, solvates, metabolites, and pharmaceutically acceptable salts or prodrugs thereof, wherein the variables are defined in the specification. The invention further relates to use of the compound, the stereisomer, the stereomer, the tautomer, oxynitrides, hydrates, solvates, metabolites, pharmaceutically acceptable salts or salt of prodrugs thereof as medicines, particularly use in preparing medicines for preventing and treating fracture and osteoporosis.


Icariin derivative Upstream and downstream

1067198-74-6 Upstream product

  • 113558-15-9

    icariside II 

  • 540-51-2

    2-bromoethanol 

  • 118525-40-9

    icaritin 

1067198-74-6 Downstream Products

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