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Benzoic acid,2-[[8-(trifluoromethyl)-4-quinolinyl]amino]-, 2,3-dihydroxypropyl ester

Another name:

CasNo: 23779-99-9 Purity: AR 98% Molecular Structure: C20H17F3N2O4

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floctafenine Basic Product Information

Product Name floctafenine CAS 23779-99-9
Synonyms Anthranilicacid, N-[8-(trifluoromethyl)-4-quinolyl]-, 2,3-dihydroxypropyl ester (8CI);Glycerol, 1-[N-[8-(trifluoromethyl)-4-quinolyl]anthranilate] (8CI); Diralgan;Floctafenin; Floctafenine; Idalon; Idarac; Novodolan; R 4138; R 4318; RU 15750 Molecular Formula C20H17 F3 N2 O4
EINECS Number 245-881-4 Molecular Structure
Appearance Light Yellow Powder
Purity AR 98%
Supply Ability

floctafenine Quality documents

floctafenine Appearance/Package/Shipping/Storage

package

storage condition

Store in cool & dry place,Keep away from strong light and heat

floctafenine Application

floctafenine literature

A new, convenient synthesis of glafenine and floctafenine

Mouzin,Cousse,Autin

, p. 54 - 55 (1980)

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Coordinating Activation Strategy-Induced Selective C?H Trifluoromethylation of Anilines

Xu, Jun,Cheng, Ke,Shen, Chao,Bai, Renren,Xie, Yuanyuan,Zhang, Pengfei

, p. 965 - 970 (2018/02/12)

A simple protocol for the synthesis of 2-(trifluoromethyl)aniline derivatives through a coordinating activation strategy was developed. The reaction showed good reactivity and gave the target products in moderate to good yields. Pleasingly, the directing group could be recovered in excellent yield. Furthermore, this strategy allowed efficient access to the synthesis of floctafenine. A single-electron-transfer mechanism was proposed to be responsible for this trifluoromethylation reaction.


floctafenine Upstream and downstream

23779-99-9 Upstream product

  • 23779-97-7

    4-chloro-8-(trifluoromethyl)quinoline 

  • 71574-35-1

    α-Glyceryl Anthranilate 

  • 118-48-9

    isatoic anhydride 

  • 10354-53-7

    N-phenylpicolinamide 

  • 88-17-5

    2-(trifluoromethyl)benzenamine 

  • 93919-57-4

    8-(trifluoromethyl)quinoline-4(1H)-one 

  • 450383-19-4

    2,2-dimethyl-5-({[2-(trifluoromethyl)phenyl]amino}methylidene)-1,3-dioxane-4,6-dione 

  • 34067-83-9

    N-(phenyl)pyrazine-2-carboxamide 

23779-99-9 Downstream Products

  • 886841-61-8

    2-oxoethyl 2-{[8-(trifluoromethyl)quinolin-4-yl]amino}benzoate 

  • 886841-69-6

    2-{[8-(trifluoromethyl)quinolin-4-yl]amino}benzohydrazide 

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