1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride Basic Product Information

Product Name	1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride	CAS	25952-53-8
Synonyms	1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride;	Molecular Formula	C8H18ClN3
EINECS Number	247-361-2	Molecular Structure
Appearance	Light Yellow Powder
Purity	99.00%
Supply Ability

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride Quality documents

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride Appearance/Package/Shipping/Storage

package

storage condition

Store in cool & dry place,Keep away from strong light and heat

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride Application

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride literature

1 - Ethyl - (3 - dimethyl aminopropyl) carbodiimide hydrochloride preparation method (by machine translation)

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Paragraph 0025; 0034; 0035; 0039; 0040; 0044, (2019/03/08)

The invention relates to a 1 - ethyl - (3 - dimethyl aminopropyl) carbodiimide hydrochloride preparation method, which belongs to the technical field of pharmaceutical intermediates. The preparation method comprises the reaction generating EDTC, prepared crude EITC, distillation fractionation, to produce an intermediate, make the EDC and to obtain the target product in seven steps. The present invention provides a preparation method, has a high product yield and purity, the operation step is simple, easy to implement, for industrial production. (by machine translation)

1 - (3-dimethylamino-propyl) - 3-ethyl carbodiimide hydrochloride preparation method

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, (2017/05/10)

The invention belongs to the field of organic chemical industry, and particularly relates to a preparation method of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride. The method comprises the following steps: enabling N,N'-dimethyl-1,3-propanediamine and carbon disulfide as raw materials to react in an organic solvent to generate an intermediate 1; enabling the intermediate 1 and ethyl chloroformate to react in the organic solvent, and preparing an intermediate 2 from triethylamine as an acid-binding agent; enabling the intermediate 2 and ethylamine to react in the organic solvent, so as to prepare an intermediate 3; adding a catalyst to the intermediate 3, oxidizing one time with an oxidant, so as to obtain a crude product 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide, extracting and separating, so as to obtain an intermediate 4; and carrying out salt exchange reaction on the intermediate 4 and hydrochloride, so as to prepare the product 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride. The method has the advantages of relatively high conversion rate and relatively high total recovery rate and is simple to operate and suitable for industrial production.

SUBSTITUTED DIHYDROCHINAZOLINES HAVING ANTIVIRAL PROPERTIES

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Page/Page column 92-93, (2008/06/13)

The invention relates to substituted dihydrochinazolines of formula (I), methods for the production thereof, and the use thereof for producing medicaments used for treating and/or preventing diseases, particularly as antiviral agents, especially against cytomegaloviruses.

Acrylamide derivatives and process for production thereof

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, (2008/06/13)

Acrylamide derivatives represented by General Formula (1) below: STR1 (One specific example of General Formula (1) is methyl (S,S)-3,3'-?3,3'-(1,4-phenylenediacryloyl)!-bis?1-chloromethyl-5-hydroxy-7-triflouromethyl-1, 2,3,6-tetrahydropyrrolo?3,2-e!indole-8-carboxylate.) The acrylamide derivatives represented by General Formula (1) is highly selective to cancer cells, less toxic, and highly active also against solid tumor.

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride Upstream and downstream

25952-53-8 Upstream product

• 628-13-7

  pyridine hydrochloride 

• 1892-57-5

  N-(3-dimethylaminopropyl)-N-ethylcarbodiimide 

• 18997-72-3

  N-(3-Dimethylamino-propyl)-dithiocarbamidsaeure 

• 27421-70-1

  3-(dimethylamino)propyl isothiocyanate 

• 109-55-7

  1-amino-3-(dimethylamino)propane 

25952-53-8 Downstream Products

• 81409-90-7

  cabergoline 

• 81409-91-8

  N-<<<3-(dimethylamino)propyl>amino>carbonyl>-N-ethyl-6-(2-propenyl)-ergoline-8β-carboxamide 

• 289903-64-6

  homovanillic acid pentafluorophenyl ester 

• 454452-97-2

  5-fluoro-2-methyl-3-(N-(S-α-hydroxylmethyl)benzyl)-indenylacetamide 

• 308833-88-7

  C₂₇H₂₇ClN₆O₂ 

• 254979-43-6

  N-(4-dimethylaminophenyl)-α-[(1,1-dimethylethoxycarbonyl)amino]-4-pentynamide 

• 689294-96-0

  tert-butyl {2-[(3-{[1-methyl-5-(tritylamino)-1H-pyrazol-4-yl]amino}-3-oxopropanoyl) amino] ethyl} carbamate 

• 757963-83-0

  5-[(2R)-2-({(2R)-2-[4-(benzyloxy)-3-(hydroxymethyl)phenyl]-2-{[tert-butyl(dimethyl)silyl]oxy}-ethyl}amino)butyl]-N-[(1R)-1-phenylethyl]-1H-indole-2-carboxamide 

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