Allyloxypolyethyleneglycol Basic Product Information

Product Name	Allyloxypolyethyleneglycol	CAS	27274-31-3
Synonyms	Glycols,polyethylene, monoallyl ether (8CI);Poly(oxy-1,2-ethanediyl), a-2-propenyl-w-hydroxy- (9CI);AE 1100;AE 20;APEG 350;Adeka Carpol LX 1383;Breox AA-PE 554H;F 6;F 6 (polyoxyalkylene);HMX 23;Nissan Uniox A 450R;Nissan Uniox PKA 5002;Nissan Uniox PKA 5003;Pluriol A 010R;Polyglycol20-10;Polyglycol A 1100;Polyglycol A 550;Polyoxyethylene monoallyl ether;Rhodasurf AAE;Rhodasurf AAE 10;SGG 01201;Uniox A 450R;Uniox PKA 5004;a-2-Propenyl-w-hydroxypoly(oxy-1,2-ethanediyl);a-Allyl-w-hydroxy poly(ethylene oxide);	Molecular Formula	C9H18O4
EINECS Number		Molecular Structure
Appearance	Light Yellow Powder
Purity	AR 98%
Supply Ability

Allyloxypolyethyleneglycol Quality documents

Allyloxypolyethyleneglycol Appearance/Package/Shipping/Storage

package

storage condition

Store in cool & dry place,Keep away from strong light and heat

Allyloxypolyethyleneglycol Application

Allyloxypolyethyleneglycol literature

Synthetic analogues of glycosylphosphatidylinositol-anchored proteins and their behavior in supported lipid bilayers

Paulick, Margot G.,Wise, Amber R.,Forstner, Martin B.,Groves, Jay T.,Bertozzi, Carolyn R.

, p. 11543 - 11550 (2007)

Positioned at the C-terminus of many eukaryotic proteins, the glycosylphosphatidylinositol (GPI) anchor is a posttranslational modification that anchors the modified proteins in the outer leaflet of the plasma membrane. GPI-anchored proteins play vital ro

Chain extender as well as preparation method and application thereof

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Paragraph 0038; 0041; 0043; 0046; 0048; 0051, (2022/01/20)

The invention relates to a chain extender. The chain extender is 3-(2-(2, 3-dihydroxy propyl) sulfo) ethyoxyl) propyl 3-(3-(tert-butyl)-4-hydroxy-5-methyl phenyl) propionate (GL), and the structural formula of the chain extender is shown in the specification. The prepared chain extender GL has an excellent toughening effect; the elongation at break of a polyurethane elastomer prepared from the GL reaches 1531.1594%, the toughness reaches 12.315% MJ/m < 2 >, the repairing efficiency reaches 103.62% after the polyurethane elastomer is repaired for 6 h at the normal temperature, and the repairing efficiency reaches 125.53% after the polyurethane elastomer is repaired for 2 h at the temperature of 80 DEG C. The prepared chain extender GL can be compounded with other reinforced chain extenders so as to be used, and the tensile strength and toughness of the polyurethane elastomer are further improved synergistically.

Non-natural amino acid and application thereof Recombinant protein and recombinant protein conjugate comprising same

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Paragraph 0094; 0098; 0099-0100, (2021/10/27)

The invention provides a non-natural amino acid. A compound represented by formula (I) or an enantiomer thereof. The invention also provides application of the non-natural amino acid. Further, the present invention also provides a protein conjugate comprising the recombinant protein and of the non-natural amino acid prepared from the recombinant protein. The non-natural amino acid provided by the invention is simple and convenient to prepare, good in safety, not prone to inactivation when inserted into a protein, high in coupling ratio with a coupling part, good in stability of the obtained conjugate, and capable of being applied to various fields, especially in preparation of recombinant protein or recombinant protein conjugate.

Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel-Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7

Zoppi, Vittoria,Hughes, Scott J.,Maniaci, Chiara,Testa, Andrea,Gmaschitz, Teresa,Wieshofer, Corinna,Koegl, Manfred,Riching, Kristin M.,Daniels, Danette L.,Spallarossa, Andrea,Ciulli, Alessio

, p. 699 - 726 (2019/01/11)

Developing PROTACs to redirect the ubiquitination activity of E3 ligases and potently degrade a target protein within cells can be a lengthy and unpredictable process, and it remains unclear whether any combination of E3 and target might be productive for degradation. We describe a probe-quality degrader for a ligase-target pair deemed unsuitable: the von Hippel-Lindau (VHL) and BRD9, a bromodomain-containing subunit of the SWI/SNF chromatin remodeling complex BAF. VHL-based degraders could be optimized from suboptimal compounds in two rounds by systematically varying conjugation patterns and linkers and monitoring cellular degradation activities, kinetic profiles, and ubiquitination, as well as ternary complex formation thermodynamics. The emerged structure-activity relationships guided the discovery of VZ185, a potent, fast, and selective degrader of BRD9 and of its close homolog BRD7. Our findings qualify a new chemical tool for BRD7/9 knockdown and provide a roadmap for PROTAC development against seemingly incompatible target-ligase combinations.

A single-mercapto double-cetyl the ether gathers glycol [...] glycolipid synthesis method (by machine translation)

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Paragraph 0062-0065, (2019/11/04)

The invention discloses a single mercapto double-cetyl [...] glycol [...] glycolipid synthesis method, characterized in that the 2, 3, 4, 6 - O - acetyl - α - D - pyran mannose the heat stability of the polyurethane in the [...][...] benzoic acid with thr

Allyloxypolyethyleneglycol Upstream and downstream

27274-31-3 Upstream product

• 75-21-8

  oxirane 

• 107-18-6

  allyl alcohol 

• 107-21-1

  ethylene glycol 

• 3984-22-3

  2-vinyl-1,3-dioxolane 

• 821-09-0

  n-Pent-4-enyl alcohol 

• 106-95-6

  allyl bromide 

• 107-07-3

  2-chloro-ethanol 

• 107-05-1

  3-chloroprop-1-ene 

27274-31-3 Downstream Products

• 116983-87-0

  maleic acid-(2-allyloxy-ethyl ester)-methyl ester 

• 15424-04-1

  2-(allyloxy)ethyl bromide 

• 70964-99-7

  acetic acid 2-allyloxyethyl ester 

• 40762-37-6

  1-(2-Cyan-ethoxy)-2-allyloxy-ethan 

• 50281-82-8

  phthalic acid bis-(2-allyloxy-ethyl ester) 

• 70965-00-3

  1-allyloxy-2-benzoyloxy-ethane 

• 91213-71-7

  2-(3-(2-Hydroxy-ethoxy)-propyl)-cyclohexanon 

• 118599-69-2

  6-(benzyloxy)-4-oxahex-1-ene 

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