Another name:2-(cyclohexylamino)ethanesulfonic acid; 2-Cyclohexylaminoethanesulfonic Acid [Good's buffer component; 2-Cyclohexylaminoethanesulfonic acid;

CasNo: 103-47-9 Purity: >98% Molecular Structure: C8H17NO3S

Add to cart

CHES Basic Product Information

Product Name CHES CAS 103-47-9
Synonyms 2-(cyclohexylamino)ethanesulfonic acid;
2-Cyclohexylaminoethanesulfonic Acid [Good's buffer component;
2-Cyclohexylaminoethanesulfonic acid;
Molecular Formula C8H17NO3S
EINECS Number 203-115-6 Molecular Structure
Purity 98%
Appearance White crystalline powder
Supply Ability 100T Per Year

CHES Quality documents

CHES Appearance/packaging/transportation/storage images


25kg/Cardboard Drum , Double plastic bag inside

Storage condition

Normal temperature 25 ℃, dark 

CHES Application

CHES (2- (N-cyclohexylamino) ethanesulfonic acid) is considered a high-quality buffer due to its self buffering properties and biocompatibility. Used to stabilize proteins without interacting with metals. The specific application is as follows:

1. A buffer for determining the activity of mannanase in Antarctic fungal isolates;

2. Buffer solution for DNA enzymatic hydrolysis and labeling of 2 '- deoxyadenosine 3' - monophosphate;

3. As a component of Wilson and Horne extraction buffer, used to characterize rat plasma enzymes.


CHES literature

Preparation method of N-cyclohexyl-2-aminoethanesulfonic acid


Paragraph 0015; 0033-0038, (2021/03/13)

The invention discloses a preparation method of N-cyclohexyl-2-aminoethanesulfonic acid, which comprises the following steps: heating cyclohexylamine, 1,2-dichloroethane and sodium sulfite to reflux in the presence of a solvent and a catalyst, reacting at reflux temperature, filtering the reaction solution after the reaction is finished, and acidifying and crystallizing the liquid to obtain the N-cyclohexyl-2-aminoethanesulfonic acid. According to the invention, with the cyclohexylamine, 1,2-dichloroethane and sodium sulfite as raw materials, the product can be prepared just through a one-potone-step process; therefore, the reaction conditions are mild, operation is easy, mastering is easy, products obtained after reaction are easy to treat, and the purity of the products is high and canreach 99% or above.

Method for synthesizing 2 - ring has sulfonic acid process


Paragraph 0035-0097, (2019/03/29)

The invention discloses a method for synthesizing 2 - ring has sulfonic acid process, comprising the following steps: the link already amine heating, then drop the heating of 2 - chloroethyl sulfonic acid sodium aqueous solution, stirring and heating to reflux, adding 1 - 3 wt % activated carbon, reflux after filtering is hot, concentrated, adding ethanol, glacial acetic acid to adjust the pH to use 5.0 - 6.0; adding the filtrate 1 - 1.5 times of the volume of ethanol, cooling, filtering; residue to heat of ethanol, reflux, then adding water, filter when it is hot, cooled to 5 - 10 °C, filtering, filter residue with ethanol washing, drying, to obtain 2 - ring has sulfonic acid. The present invention provides synthesis of relatively high process yield, purity is good.

Isolation of nucleic acids


, (2008/06/13)

A method for extracting nucleic acids from a biological material such as blood comprises contacting the mixture with a material at a pH such that the material is positively charged and will bind negatively charged nucleic acids and then eluting the nucleic acids at a pH when the said materials possess a neutral or negative charge to release the nucleic acids. The nucleic acids can be removed under mildly alkaline conditions to the maintain integrity of the nucleic acids and to allow retrieval of the nucleic acids in reagents that are immediately compatible with either storage or analytical testing.

Zwitterionic compounds and their n-halo derivatives for use in the treatment of clinical conditions


, (2008/06/13)

Zwitterionic compounds selected from: taurine (2-aminoethanesulphonic acid), 2(N-morpholino)ethanesulphonic acid (MES), N-(2-acetamido)iminodiacetic acid (ADA), piperazine-N,N'bis(2-ethanesulphonic acid (PIPES), N-(2-acetamido)-2-aminoethanesulphonic acid (ACES), N,N-bis(2-hydroxyethyl)-2-aminoethanesulphonic acid (BES), 3-(N-morpholino)propanesulphonic (MOPS), N-N[tris(hydroxymethyl)-methyl]-2-aminoethanesulphonic acid (TES), N-2-hydroxyethylpiperazine-N'-2-ethanesulphonic acid (HEPES), N-2-hydroxyethylpiperazine-N'3-propanesulphonic acid (H)EPPS), 2-(cyclohexylamino)ethanesulphonic acid (CHES) or 3-(cyclohexylamino)propanesulphonic acid (CAPS), and their N-halo derivatives can be used separately or in combination in the treatment of related clinical conditions by stimulating myeloperoxidase activity, which in turn stimulates hypochlorous acid production in vivo, which leads inter alia to enhanced leukotriene inactivation.

CHES Upstream and downstream

103-47-9 Upstream product

  • 3851-91-0

    ethene-sulfonate d'isopropyle 

  • 108-91-8


  • 15484-44-3

    Na-salt of 2-chloroethane-1-sulfonic acid 

  • 107-06-2


103-47-9 Downstream Products

  • 85582-50-9

    2-cyclohexyl-1,2-thiazetidine 1,1-dioxide 

  • 148588-19-6

    (E)-4-(α-amino-4-chlorobenzylidene)-2-cyclohexyl-1,2-thiazetidine 1,1-dioxide 

  • 1612259-41-2


  • 122732-69-8


  • 122732-70-1


  • 113599-04-5


Related Products

Online message

Please leave us a message or contact us using the following methods. We will reply to you as soon as possible and provide you with the most sincere service, thank you.

Hangzhou Office: Hangzhou Office:Suite#210A,No.1 Building, No.182 Zhaohui Road, Xiacheng District, Hangzhou City, Zhejiang Province,China.

Tel: +(86) 0571 8716 2326

Fax: +(86) 571 8719 1975

Phone: +(86) 177 6713 0763


WhatsApp:   +(86)177 6713 0763

Requirement description
*Product Name
*Company Name
Destination Port
Payment Method
Delivery Time
*Other Description
*Verification code:
The product has been successfully added to the shopping cart
Added to shopping cart, please do not add again
After a successful purchase, our staff will contact you within 24 hours.
The message was successful, and our staff will contact you within 24 hours.