6-cyclohexylhexan-1-ol literature
Free-radical anti-Markovnikov hydroalkylation of unactivated alkenes with simple alkanes
Tian, Yunfei,Ling, Anbo,Fang, Ren,Tan, Ren Xiang,Liu, Zhong-Quan
supporting information, p. 3432 - 3435 (2018/08/07)
A Cu(ii)-mediated radical anti-Markovnikov hydroalkylation of unactivated alkenes with simple alkanes via selective C(sp3)-H bond cleavage was achieved. This reaction features high site-selectivity diverse functional group tolerance, and scalability.
Chain-modified pyridino-N substituted nicotine compounds for use in the treatment of CNS pathologies
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Page 10-11, (2010/02/05)
Compounds for treating abuse of nicotinic receptor agonists, addiction to psychostimulant drugs, addiction to opiates, addiction to alcohol, addiction to tobacco products, addiction to nicotine, schizophrenia and related diseases, depression and related conditions, Alzheimer's disease, Parkinson's disease, irritable bowel syndrome, and colitis. The compounds competitively inhibit central nervous system acting nicotinic receptor agonists and act at the putative α3β2* and α4β2 neuronal nicotinic receptors in the central nervous system.
Synthesis of diaminobutane derivatives as potent Ca2+-permeable AMPA receptor antagonists
Yoneda, Yoshiyuki,Kawajiri, Shinichi,Sugimura, Masunobu,Osanai, Ken,Kito, Fusako,Ota, Emi,Mimura, Tetuya
, p. 2663 - 2666 (2007/10/03)
We synthesized diaminobutane derivatives as potent Ca2+-permeable AMPA receptor antagonists with non-hypotensive activity. Compound 10c showed selective Ca2+-permeable AMPA receptor antagonist activity and neuroprotective effects in transient global ischemia models in gerbils.